great post -
great way to look at Laura's connection to Brain through the theory - so much of her relationship to Brendan involves how much she is or isn't getting to him.
if we look at it this way we can actually gauge her effect on Brendan not just by his reactions to her but also by when and how much she speaks to brain. She doesn't speak to Brain around the time she and Brendan hook up because arguably, something other than Brendan's brain takes over.
In a much belated response to Noah: Em requesting Brendan's locker combo from Brain can be explained in a similar way. Brian telling Brendan about Em's request is just Brendan using his brain to remember that he had himself given his locker combo to Em at a previous point. Hence, Em's note.
Also; the Lara discovering the brendan-brain connection speaks to both the metaphorical brain and lara's ability.
1) Her getting to brendan's brain as an example of how close she is to getting brendan under her thumb,
2) Her discovering the person brain as an example of how she knows and can find out about everyone (not even teh Pin seems to have a knowledge of Brain).